Another interesting one…
I had to remove LoopMIDI and replace it with the new MS MIDI loopback on windows 11 which caused some issues with DMXDesktop.
While testing without my X32R connected (so the standard ASIO driver is in use) the track that sends scene changes failed to transmit even though MIDI clock was sending. Reconnecting the X32R solved the problem so it appears that MIDI devices are not reconnected correctly when an expected one is missing.