Since I get a lot of crashes I set it to auto-save in 1 minute. I am mixing 90 audio track session and I can work max 40 seconds in a minute. This is ridiculous. The auto-save is killing all of my workflow. In any other DAWs that I use (Pro Tools and Ableton) there is no such thing!
Make sure you have the latest Cubase update and installed and all plug-ins up-to-date, please.
Could you attach some of the DMP files (Documents/Steinberg/Crash Dumps folder)? Maybe we will find what is causing the crashes.