Hi, I will clarify.
Not talking at all about applications. 32 bit application support was dropped in Catalina onwards and only 64 bit software is allowed. I am talking about 32 bit non floating point BIT RATE support. There are two main drivers for AXR4 - normal and high precision. Only Steinberg products allow access to 32 bit non floating point bit rate support and this is accessed via the High Precision driver only. Part of the marketing campaign of the AXR4 was the use of 32 bit bit rate - a whole deal was made about it, and now I think in Big Sur it will not work at least not according to the Steinberg compatibility document - they noted they need to talk to Apple about it, but I have yet seen any update on this and fear it is neglected all together.
I see that Steinberg hardly ever participates in this forum, and the lack of discussion and support is problematic to say the least. Also, I have posted a question in the forum asking people who have the USB version of AXR4 to see if with the new updated Big Sur drivers the High Precision driver works or not. No answers as of yet.