I may have found what was causing my kernel panics, so I wanted to post an update. I had been using an application called SoundSource by Rogue Amoeba to control application volume and even add IK Multimedia’s ARC System to certain applications. It’s a neat program that provides for a lot of flexibility and I did not have an issue while using the Persons Quantum. I decided to not run SoundSource for the past 3 days with only the AXR4U as my audio interface. I’ve had no crashes and even noticed a latency improvement, which makes sense. Still hoping for 32bit operation to return to Big Sur, and hopefully some additional onboard DSP but happy to not have any crashes!