All plugins in project bypassed?

Hi folks,
Somehow when using automation preview mode, setting and punching stuff around, all my plugins in the project get bypassed.
It happened to me I think 5 times and I still did not get exactly what is triggering it.
Is there a hidden key command for this that I am accidentally pressing, or an automation weirdness?
It’s very annoying to sit and enable back each and every plugin in an 100+ track project.

It sounds familiar. Could you be suffering from this:

?

Thanks, I’ll give it a try!