Fonts and spacing are just one part of the total layout, to be sure, but: I’ve come to appreciate that there are a number of very seriously font-aware Dorico users (and, indeed music font designers) here in the forum. They can meaningfully say things like “with this font, default quarter note spacing looks best at 3.7, whereas with this other 3.5 is better.”
There have also been a number of great threads about Dorico’s vertical spacing options, etc.
After you’ve spent some time arriving at favorite fonts, you might search the forum for some of those past conversations. A quick search with the term “House Style” turned up this little gem (started by none other than @k_b who first responded here):