Apogee Quartet problem

I can’t get Cubase LE to play nice with my Apogee Quartet. The studio setup window allows me to select the Quartet driver, and it shows the ports, but with the exception of Line Out 1 & 2, is shows them all as inactive. The project window shows Audio Inputs Not Connected. Apogee Maestro shows the Quartet as active and responds to inputs. So does system preferences audio.

I’m running on an old (late 2009) Mac mini with osX 10.11.6 El Capitan. It meets/exceeds all specs for both the Quartet and Cubase. My Apogee firmware us up to date and I’m running Cubase LE 9.5.41.

Has anybody else had a similar problem? Any idea what I’m doing wrong?