Asio Guard

Hi, I’m running 4 vst which have always worked fine, but today for some reason I started getting VST connection lost, when I go into plugin manager I have noticed that all my plugins say “Asio guard active” but the 2 plugins that keep crashing on me in the same field say “no” I’m running win7 64 and the plugins causing this are nexus and omnisphere. could anyone advise me please, again I stress they have all been working fine up until today? quite frustrating actually, mm just tried it again and now its freezing the plugin and sustaining the note and then crashes CB pro 8
thank you so much

Omnisphere 2 troubleshooting states that Asio Guard is incompatible with it. Go to Devices Plugin Manager select Omnisphere and turn off Asio Guard in the lowest box Plugin information