Audio output issue - Cubase 9.5 LE - M-Audio M-Track 2x2M

Hello Friends, I have just bought an M-Audio M-Track 2x2M interface, and I also got a Cubase 9.5 LE licence in the box. The M-Audio interface itself works fine with my computer, but when I try to use a plug-in (Amplitube 4, Guitar Rig. 5) in Cubase LE, the M-Audio M-Track 2x2M ASIO driver not works at all: I have input signal from my guitar (throught the M-Audio card) in Cubase, but plug-ins are silenced, they have no input, and there is no output signal at all.
When I switch ASIO driver from M-Audio driver to Generic Low Latency ASIO driver, plug-ins are work, but whit 40ms latency, and the other applications of my computer have no voice.
I have set up everything as shown in Steinberg and M-Audio tutorials, and reinstalled the programs and drivers, but nothing has helped so far.

Hi and welcome,

AmpliTube is quite CPU load hungry. Try to increase your Audio Device Buffer Size, please.