Null perfectly with a number of plugins, not the standard compressor.
Auto make-up gain can make it worse, but as far as I can tell, it is the algorithm that reacts slightly different to the audio.
I tested different plugins. And those who cancel each other in Studio One and Maschine doesn’t cancel itself in Cubase.
I don’t think that Cubases standard compressor is that advanced to react differently to the same drum loop. In addition to that it doesn’t have any emulated “analog” noise which affect self cancellation.
Have you tried it, can you confirm this behavior?