Hi. I’d like to respectfully report that there’s a (big) problem in the way the Transpose tool has been reworked. In this piece, the section in B can no longer be transposed in B flat. I would need to select Unison, Down, Augmented (damn, I don’t like the order of things in that window…) and this is not possible. So I tried using the right hand tool. And if I put from B to B flat… nothing happens, because Dorico 4.0 cannot do it. Please fix it 
Joseph, my advice is the good one here but cannot be applied because of that nasty bug.
[Edit] Worse : if I uncheck Transpose key signatures, the right hand tool sets the transposition to +1/12 semitones Augmented Unison. The problem is you’ve removed (rightly) Diminished Unison, but we need to have the Down direction for Augmented Unison. Funny though, if I apply it, it really transposes -1/12 as wished. Ok, some work is needed. Sorry to bring those bad news 
[Re-Edit] : WORKAROUND. To transpose an augmented unison down, uncheck the Transpose Key signatures option, use the right hand tool (G to G flat, for instance, and apply) then CHECK the Transpose button again, and don’t worry about what’s showing in that Transpose window. Apply and it’s done.
Here’s your Dorico file transposed (three different sections, augmented unison, minor second, augmented unison) :
ende v2.dorico (1.1 MB)
Usually, it’s really fast (because the Transpose tool worked well, although with that strange diminished unison). I’m really confident it will work perfectly when the team corrects the glitches.
[Edit 3] I am sorry: I misread your first post and thought you wanted to transpose a semi-tone down. This is fortunate, since I would not have discovered the transposing problem by a (former) diminished unison. But the file I sent is useless, since it’s all transposed down!
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