Can you help me

I have an Oxygen 61 M-AUDIO and Cubase 10.5, but can not find instruments, and lack an asio driver. I’m a noob for this.

You need a driver for M-Audio Oxygen 61

See here. depends if yours is silver or blue model. Install driver then your computer should see it.

For Asio download asio4all

Hope this solves your problem

Thanks for your post, at its did not solved my problem. Its seem that the “windows G5 wavetable synth” are inactive?

I installed Asio4all An thats work, but still have problems with instrument, how do it solved this problem?

Which VST Instrument are you using with your midi controller?