One thing I noticed was that “jog” won’t really go by frame in Cubase/Nuendo. When binding to ‘step by frame’ it’ll actually trigger more than one step per “click” or “detent” of the controller. So I reassigned the wheel to zoom in/out instead.
Generally I recommend picking one type of action per key or jog/shuttle, and then add something logical in addition to that using modifier keys. So for example:
The wheel sends key command that targets increase/decrease fade in.
Then program your key commands so that a modifier (for example ctrl (mac)) makes the same wheel turn do the same thing but for the fade out. So same controller item does the same thing but different places. And look at your keyboard and lay it out logically, so on a mac use command for “in” and control for “out”, because the keys are located left/right just like in/out on screen…
I guess just generally think of how you have your hands when you work… and what tasks you perform the most that could use some help…
maybe that’s a starting point…