Does your Cubase quit properly? Isn’t there a silent crash while quit? Can you find any crash dump file (located in Documents/Steinberg/Crash Dumps folder)?
The same issue continues… losing Control Room settings. However what I am noticing now is the exploding size of the ControlRoomPresets.pxml file.
Under 9.5 its around 560 KB. I used that to replace the one in the Cubase 10-64 folder. I opened up Cubase, loaded my latest template and then just QUIT.
At first the pxml file goes to 0 KB then after a few moments (Cubase still quitting) the pxml file file grew to 29,651KB!!!
I was trying to bring over my settings from 9.5 and in order not to trash the original files (mainly RAMPresets.xml and ControlRoomPresets.pxml) I would rename the V10 files to xRAMPresets.xml and xControlRoomPresets,pxml - leaving them in the Preset folder - and then copy the 9.5 files over to the same folder (Presets).
I suspected that Cubase looks for any file with ControlRoomPreset in that folder and gets messed up and loses the Control Room connections-
So I removed all my “renamed/saved” files from that folder and then copied over the 9.5 versions.
And now Cubase functions as expected, recalling all the Audio Connections settings!