Controlling audio output on UR22 mkII

I have an unusual situation. I have a client that uses the UR22 mkII for her virtual and hybrid programs.

We use vMix production software for running the program. It takes in mics and sends their signal out to remote and in-room participants.

We send the audio out of vMix to the house speakers through the outputs on the UR22. Is there a way to control the mix going out of the UR22 to the house speakers? I’ve created an audio bus in vMix that creates a unique mix, but even though it is set to send this mix out to the room, it seems that all audio signals are going out as opposed to the selected mix.

I hope I’m explaining this correctly. I appreciate any advice for making this more reliable.