2 weeks ago I updated to Nuendo Live v1.1 for use with CL console. Also, updated console/rio firmware, console extension for nuendo, etc. Nuendo now crashes regularly, but intermittently. Sometimes it will crash after a few seconds, sometimes a few minutes, sometimes an hour. Sometimes I get the too many tracks recording error, sometimes it just stops responding and I get the pinwheel.
I am recording 48 tracks to an external Thunderbolt Lacie drive with 500gb currently available.