CUBASE 10.5 Insert effects - NO SOUND- NOT WORKING INSERTS

Hi

I didn’t find a similar problem on the forum here. Today, Cubase 10.5 PRO started doing the problem that imported audio tracks (MONO, 48kHz, 24bit) ) do not play sound into the Insert effects, so Insert effects on MONO tracks do not work. Neither the factory plugins nor the 3rd plugins. What do I do with this? All my plugin its legal, and up to date (UAD, WAVES, SONNOX) E-licencer working, but I found a trial license there that I did not activate.
Thank You for help!