Cubase 12.0.50 on Apple silicon using Rosetta : No audio?

With rosetta OFF my audio interface works. But most of my plugins don’t.
With rosetta ON, my audio interface is seen and seems to be connected but no audio reaches the audio interface. (Other DAWs do not have this issue.)

Any ideas? No it’s not the setup. yes I checked studio and audio connections.
The same settings files load fine in rosetta-off (m1 native) mode and audio works fine.
Screen Shot 2022-11-13 at 10.57.58 PM

Could it be a security setting in the OS?

It appears to be a bug in Mac OS Monterey.
Rebooting fixes it.