You are not alone on this. I had 64 stereo stereo output channels with all custom labels typed in. I saved, restarted, and it is all gone. That is just one of many issues. Hanging on shutdown at least 50% of the time.
This Cubase 12 isnt even Beta ready. I dont care about the fan boys and their praise of CB12. I have a standard modern DAW machine 10700k. Nothing crazy.
I dont have any issues running Studio One or any of my VSTs. Guess what I am doing? Uninstalling this POS and giving up. I am tired of paying for Alpha releases that just plain suck my time.