Cubase 3 Version 3.8.2 problem Interface Flow8 Behringer

I have the following problem:
I am using Cubase 3 version 3.8.2 and would like to connect the Behringer Flow8 interface.

The interface is recognized, but there is a very loud noise.
48 kHz is set.
How can I connect the interface to Cubase 3?

The cable connectors have been tested several times. Routing has been set up.