[Cubase 5.5.3] No Sound with Scarlett Focusrite 6i6 1st Gen

Hi everyone,

I have an issue which came out of nowhere yesterday:
My configuration was running fine, nothing crashed, I just shut down the computer the other night and started Cubase the next day. No meters are moving anymore and I get no Sound at all in Cubase. System sounds, and everything else but Cubase is working fine. I spent hours trying to fix the issue. I checked all the obvious things like routing, Device setup, start a new project, load older projects, update drivers (I now have the newest beta drivers as similar issues seem to be known) - all to no avail.

I’m getting sound when switching to my internal Soundcard and I even get a working audio file when I do a mixdown with my Scarlett selected as device.

My Specs:

Windows 10 x64
AMD Ryzen 7 (since there seems to be an issue with AMD processors)
Cubase 5.5.3.
Scarlet Focusrite 1st Gen (Mix Controll v 1.9, driver 3.2, Firmware 1056)

I’m going insane here. This came out of nowhere and everything was working fine for months before this happened. I changed nothing in my hardware setup and afaik there wasn’t even a Windows update installed in the meantime…
Anybody have any ideas? I’d be eternally gratefull!

Hi svthiele,

Sorry to hear that you’re having some problems.

Do you happen to have either AVG or Avast anti-virus software installed? If so this may be the cause of the issue, please see the following article from our Help Centre: https://support.focusrite.com/hc/en-gb/articles/115003109265-1st-Gen-Scarlett-interfaces-No-playback-or-metering-from-ASIO-applications-

If you don’t have AVG or Avast installed or uninstalling them does not fix your issue, please get in touch with us directly if you haven’t already and we’ll do everything we can to help: https://support.focusrite.com/hc/en-gb/requests/new

Jack // Focusrite Technical Support