I know others have asked about this sort of issue before so I therefore did a search for any solutions in advance but I couldn’t find one.
So, here it goes. I’m running Cubase 5 LE (which I got with Zoom) with a Focusrite Scarlett 18i20 on W7 64bit. I’m able to record a signal okay, but I can’t get any playback. I’ve configured the ‘Device Setup’ correctly, it seems to me. The VTS Audio System is set to ‘Focusrite USB 2.0 Audio Driver’ and all the ports are listed. Mon 1 and Mon 2 are ‘Active’. In the ‘VST Connections’ section, the outputs tab lists ‘Stereo Out’ Mon 1 (left) and Mon 2 (right). The Audio Device listed is ‘Focusrite USB 2.0 Audio Driver’.
The Scarlet MixControl suggests that the DAW and interface are talking to each other, in that changes to the buffer length in Devices>Device Settings>Control Panel are reflected in the MixControl ‘Settings’ Panel. All the output channels in MixControl are set to ‘grey’ so they are full volume and unattenuated and I’m monitoring off Volume 1 from the main headphone outputs. I can get playback and monitoring output from the Mixcraft 5 DAW, but nothing from Cubase 5 LE.