Cubase 5 startup problem

Hi all.
Been running Cubase 5 for sometime without any probs. Unfortunately Ive foolishly added one of the large files to the plug in path file. (either documents or programs, cant remember which) . Now on start up its running through 100`s of irrelivent files and eventually crashing. How can I edit the plug in path file without starting up Cubase to reverse this ??