Cubase 9.5 and RME ADI-2 Pro Compatibility

May I mixing a project with RME ADI-2 Pro in Cubase? Only with it divice.

No.
The ADI-2 is a AD/DA-converter, not a soundcard.
You would need something to connect it to that has working ASIO drivers and S/Pdif, AES or ADAT connections.