Mac or pc? What audio interface are you using? Have you tried raising the buffers for the interface. If a pc have you optimised it for audio? Are you using the steinberg power plan? Try running latencyMon (google it) and see if you have a bottleneck causing the glitches.
Ok so have you looked at the other things I mentioned? You don’t say if it’s a desktop or laptop? If it’s a desktop then disable onboard audio in bios and anything else that you don’t need enabled like wi fi and Bluetooth (I use wired Ethernet)