Cubase Essentail 5 Crashing

Hey, I would appreciate anyones help with a problem I am having with Cubase Essential 5.

I can load up Cubase but as soon as I click my mouse anywhere on cubases interface the programme crashes, becomes unresponsive and I have to end it through control panel.

I have installed windows and cubase fresh with no resolve, I still have no idea what is wrong, I am yet to come up with a work around either.

I am running win 7 64bit
PC - intel i7, 12GB RAM
M-audio profire 2626 with latest drivers.

Any help would be greatly appreciated!! :smiley: