Cubase Performance + Crash Issue

I’m experiencing graphic performance issues – I have a two monitor setup. One monitor works fine (no latency and the other is slow (refresh and serious mouse lag). Also when I bootup Cubase; my Macbook Pro flickers, but then stabilizes.

Other Issues:

When I am playing back a project my CPU performance meter jumps up and down.
If I leave a project open (say overnight) then try playing it back – Cubase always freezes and I must Force Quit the Program.

My system:

MacBook Pro (late 2011)
Latest Version of Cubase 9
2.8 Ghz Core i7
16 GB Ram
Graphics Card: Intel HD Graphics 3000 512MB
SSD Drive

Audio Interface: Motu 8 Pre

Running MiniLab MK II & UAD-2 Satellite


Please, look at this thread.