Cubase Pro 13 no longer retains Direct Monitoring set

Since upgrading to Cubase Pro 13 on Windows 10 for my Yamaha Steinberg FW ASIO interface, the Direct Monitoring selection no longer retains it’s setting, even when re-opening a saved file.

This could be caused by a corruption in the Defaults.xml file in the User Settings Data Folder.

You can rule that out by starting in Cubase Safe Mode with disabled preferences

OK. I’ll try that. Will the setting get saved by default in Safe Mode?