Dual boot the OS and then its the same hardware, and with some stuff disabled, then there is no interference from non-music related stuff. I definitely wouldn’t mix it all into one OS.
In my case the other OS is used for numerical programming as is the GPU on the graphics card (and games )
This is almost certainly related to the NVIDIA driver + Cubase 8 combo as triggering a screen refresh makes the spikes much worse. Unfortunately anyone with a 900 series card can’t go back to the earlier driver versions that didn’t exhibit the problem we are seeing. Still there are folks with the problem even without this combo so its all a bit odd. I keep meaning to install Cubase 7.5 again alongside the 8 to see what its behaviour is like with the new card. just a bit concerned it might break everything! I may back things up and try it again on the weekend.
My guess is it will be optimised and fixed eventually. In the meantime a clean install got me back down to 64 samples latency with bursts jumping up to 60%, sometimes more on the realtime perf meter. But ASIO guard comes into its own in this situation and for my current usage this all works well enough. The older NVIDIA 670 card and older drivers worked down around 20% under similar load without bursts.