Cubase takes forever to play sound after restart

Hey, Im using cubase 10 with iMac 27" 16GB Ram and i5.
Im using the UR22mkII audio interface.
Everytime Im turning Cubase on it takes forever to play sound, i need to delete my outputs and create them again a few times and then It’ll work.
What can I do to solve this problem? It really bugs me and I can’t work like that.

Please help!!

Hi,

Could you try in Cubase Safe Start Mode, please?