Had to do some edits in a score created with 2.1, opened with 2.2.
In 2.1 the cue label position in engraving settings did not work as expected, so I had to do quite much manual editing. However, it seems this has been fixed in 2.2, but made my cue labels reposition themselves.
Yes, I should have opened the file in 2.1 but I noticed too late. Anyway I just mention it here in case someone else might run into the same problem.