experiencing difficulty in changing the wave file

I had a couple of difficulties at the moment through adobe premiere video editing, audio recording from the camera was not good. I tried switching the wav file to adobe audition software nuendo 3. after my edit, then I go back to wav 16bit mixdown. wav file when I return back to the adobe audition turns between video images and audio wav from nuendo not the same.

How does the solution to wave file I can run the same with video images that I have edited in adobe premiere?

what about about who should be set so that edits my wave of nuendo 3 moved to adobe premiere can run simultaneously?

sorry my english is rather less good.
for your attention I thank you.