Feedback loop

I’m using Cubase pro 10, sometimes when I have a reverb on a insert it’ll work fine for a while and then suddenly start creating feedback loops, spiking volume, white noise. This happens on multiple channels with different reverb FX.

All my plugins are legal and paid for, routing is all OK, I can’t find a reason for this happening :confused:

If anyone knows a solution or any ideas I’d appreciate some help!