Current most seductive pipe dream:
Offline processes can take advantage of our bountiful multiprocessors and run in the background without bringing Nuendo to a halt.
I already have a second computer on hand for big-project RX batches, but I still lose cumulative hours waiting for processes to complete and Nuendo to free up again.
Of course I have no idea what would be involved to implement such a feature. But it would save days, if not weeks, out of the year!