Come on guys, you can put one and one together, no?
Are you using a lot of vst3 plugins with low latency, yes or no?
A lot of VST2 plugins?
So only this information can give you a clue if vst3 suspend is applicable for you or not.
And best of all, just try the different settings.
Same for ASIO guard.
The description in the manual should give you enough clues if you need it or not.
The ASIO-Guard allows you to shift as much processing as possible from the ASIO real time path to the ASIO-Guard processing path. This results in a more stable system.
The ASIO-Guard allows you to preprocess all channels as well as VST instruments that do not need to be calculated in real time. This leads to fewer dropouts, the ability to process more tracks or plug-ins, and the ability to use smaller buffer sizes.
High ASIO-Guard levels lead to an increased ASIO-Guard latency. When you adjust a volume fader, for example, you will hear the parameter changes with a slight delay. The ASIO-Guard latency, in contrast to the latency of the audio hardware, is independent from live input.
The ASIO-Guard cannot be used for:
Real time-dependent signals
External effects and instruments
Same thing: test and tweak to your linkings.
I have machines where activating ASIO guard gives me better performance, I have machines that suffer from it.
And to conclude:
I suggested to check if those settings were not changed during the upgrade.
The proper answer would be: Yes, or no.
On that basis we can try to identify the problem.