Iconnectivity mioxl cubase crashs

ive got a iconnectity mioxl and ive got 12 midi synths connected too it it will run ok for a few channels but i can see cubase sending midi pulses out.
if i try change tempo or start doing anything in cubase then cubase frezes and crashes.

can anyone help?

Wonder if you’ve got a MIDI loop setup in your MioXL config - like a feedback loop.