Insert effect & active

Hello I’m using Cubase 11 pro, when I insert any effect it does not become , see attached pic.
This problem has just started to happen now I don’t know how to resolve.
If I open any other projects the effect are active & work good, it’s just in this project.
https://ibb.co/9NGL21P

Hi,

Make sure, the Constrain Delay Compensation is disabled, please.