Well, for a silly question, there certainly has been an awful lot of replies. Might I say that personally I shut down my computer every day. My Cubase 6 operates like a charm without any bugs, so it seems. I am totally happy the way it is running.
I always shut down both my PC and laptop whenever I’m done. That means I boot them a number of times each day. I can’t see why you wouldn’t do that, it takes 20 seconds or so