Key commands disappearing and reappearing

Hi there,
I keep having key commands that won’t work when opening Dorico. If I restart the program, they respond again but some new ones stop working and cannot be triggered neither by key command or by stream deck, but are still clickable in the panels. The non working commands seem to be entirely random and I cannot detect any pattern.
By the way, nearly all of my key commands are my own, not Dorico’s default. Normally, everything works fine even though this behavior has occurred before. It’s seems to get worse with the score getting bigger.
Anybody had the same problem and, hopefully, a solution?