Latency

I have an issue with latency.
The computer meets the specs, except the sound Card, but the workaround is a PerSonus AudioBox iTwo (so I’ve been told)
The keyboard is recording in audio, without any issues. But when recording the guitar, latency is really bad, and in mono.
The problem starts when I hit the record botton. If I am not recording, there is no latency.

Any ideas on why it’s in mono, and why I have so many issues with latency ?
Thnx
Freddy