Hello group!
Long time user, first time poster 
I’ve had this issue for a long time, and instead of getting to the bottom of it, I’ve simply used some horrible workarounds. With a big deadline and a high pressure project, I’m finally ready to figure this thing out. So here goes!
VIDEO OF THE ISSUE=============
VIDEO OF THE ISSUE=============
Some of my favorite NI/Kontakt Loop-based Instruments have exhibited this weird behaviour. Real-time MIDI performances sound as expected, but when I playback that same material in Cubase, the instruments jump mid-loop. NOTHING I do with the mid has the desired effect. Shifting notes around does nothing! All the new NI Guitar Strummers exhibit this , and several of the awesome Sonokinetic libraries, such as Minimal and WW/Strings Ostinato series.
Cubase 10.5 on a Windows 10 PC!
Thank you so much for weighing on this. I’m desperate for an answer 