Cubase 12 Pro is losing the configuration of inputs and outputs everytime I change the buffer size. It says “missing output”, then I manually have to set it back. I’m using Foscusrite 18i20 3rd gen. Any ideas? Thanks!
Most probably this would be the driver issue.
I would try to reinstall the driver as administrator.
I would recommend to use the Control Room. The setup is stored globally, not in the project. That might help.