Missing tracks after reopening saved files

I’m having a periodic issue of late where saved Nuendo projects are missing numerous tracks when reopened. There is no reporting of file corruption either when saving or opening said files but substantial amounts of data is missing or not displaying for some reason. I’ve been trying to duplicate the issue but can’t isolate what is causing it. I’ve seen it happen on new files, created with Nuendo 5.5.5 and older files opened and re-saved as 5.5.5 projects.

In years of Nuendo use I’ve never seen such behaviour. Has anyone else seen this? Any clues as to what’s causing the corruption?

I’m running OSX 10.7.5 on a MacBook Pro, Nuendo 5.5.5

I have just started using the mac book pro and I have had the same issues. Any luck?