Monitor button on transport causes feedback

When I press the monitor button on transport I get awful feedback.

Monitor on transport? More valid info please!

Transport Panel

I’m sorry it’s the speaker icon in the input/output channels window.

Which input/output channels window? DspMixFx?
You posted in the hardware forum.

So what happens when you do what?
What is connected? Which device? Windows? Mac?

I thought it has something to do with my old ur44. I connected my Yamaha mixer to my ur44 according to YouTube video. It told me to connect my mics to mixer then stereo out to ur44 . I connected my mixer to inputs 1 and 2 . Video told me to turn ur44 inputs 1 and 2 and turn ur44 input all the way up. Video also said to turn output aof ur44 to computer all the way up. I am trying to use the dsp software.

Sorry, your description is too confusing.
YouTube isn’t right in everything. Ask your YouTube star what is wrong.

Next time, provide more information in the first place, please.
Mixer model, software involved, hardware involved, what is the goal…

After 4 posts, I still have no idea what you are trying to do.

I’m sorry, I don’t know what I am doing. Just an old retired musician trying to make a recording for family.

That’s obvious. But asking for assistance isn’t a bad thing.
But you could provide more information so that we get an impression what kind of help do you need.
Try to sort yourself and post again.