I had my first session yesterday with Cubase 8 and my MR816csx. I experienced more and more dropouts as the day progressed, and at the same buffer setting where Cubase 7.5 seems to run just fine (256 samples). At one point, the dropout was permanent, all sound being stopped, despite the fact that Cubase continued to run and respond normally (except for no sound) and no indication of the hardware driver stopping. I closed and reopened Cubase without rebooting, and the sound was working again. The performance meter offered no help, indeed, there was virtually no indication of stress on the system, with the meters both just barely bumping above zero.
I haven’t tried the various suggestions for improving performance. Later today, I hope. Just an early report and question. Anybody else having issues with C8?