I’m running Cubase 10.5 on Mac mini M1, seems to be running just fine with inbuilt audio.
Bought a UR22C which works in Big Sur, but Cubase freezes and UR-C control panel does not find the card.
Will return the UR22C and buy something else, any tips?
Sooo, I just uninstalled all drivers and UR22C software, and now it works just fine without drivers, both in system and Cubase 
Weird, I got the same setup and it works just fine with cubase 11 pro. Except for the DSPMixFX.