Yes Mackie will reflect the Nuendo mixer. You can set up mixer saved nuendo mixer views and trigger them directly from the control surface. The faders will always match what you are seeing. Truth be told, I was really disappointed at first that Avid didn’t do this. Avid has a different approach called Layouts. Lay outs take more time to set up but you can trigger them from the Control or the Transport. Layouts are saved with the project file. A major downside to Layouts is, (I have 12 faders) I can’t build a layout that is more than 12 faders and keep it useful. When you are in a layout, you can no longer bank. So I use it sparingly and it’s a big reason why I’m getting another MC mix (or 2)
As far as executing the idea you are describing goes, you can use either controller and still do it using the Project Logical Editor. If all brass channels have the name BRASS in them, you can tell PLE to find and select “brass” and mute them. You could have that whole thing on a single button that is completely independent of what your faders look like.
For example, I have buttons that will select all tracks that have “FX.a” in the name. That same button also brings up a panel of new controls on my screen, like, mute,solo, link, unlink, select all, group, lock etc etc etc. You can tell the Mackie F buttons to trigger these also.
It doesn’t matter where I am in the session, this button will always select my FX.a tracks. I have a couple pages of these. I have another group of pages that just names tracks… If I find I need a couple more dialog tracks in DX.c group… I just add them, select all DX.c plus the new tracks and hit the rename button… all the tracks will be renamed and numbered, colored, and the new tracks will be part of the matrix of commands.
The whole system takes a bit to set up, but once it’s done, you can stay in that creative mind set and just work