Think I am going for the new Asus Z590-P Motherboard. This is a little more expensive but allows a future upgrade to 11th gen CPU. Also this has an additional M.2 port which is PCIe 4 so allows me to fit the Samsung 980 Pro (7KMbs/5KMbs)units 
They are currently Pre-Order but I can wait.
Edit: Bugger, just noticed will also need 11th gen CPU. So back to original plan 
As we say in Germany: here is my mustard 
Reading through the planned build it looks like a decent one, not even going into any Intel vs AMD discussions. Both have good things to offer for our needs. About mainboard strategy: I made a choice in the direction not to purchase the highest version of a board in means of addtional stuff like Wifi, 2nd NIC, etc. since Iād anyway disable all what I donāt want and need from the BIOS
Not sure about PCIx4 support for storage but even with Gen2 x3 / Gen3 x3 is all works fast enough for large projects and samples. I am using EVO 970 Plus 500 GB in GEN3 x4 mode and it features 3,5GB r/w speed approx. and a really high IOPS. But I also use SATA6 SSDs and all works like a charm. With RAM speed I just go the default but highes speed, no OC experiments just for +1% of performance in a benchmark. Here goes stability over performance. I know with Intel and AMD you have a choice of chipsets, highend (the X ones), value for money (the B ones). I decied for a B chipset because the X version required a fan, these tiny high speed troublemakers. As I want a silent DAW I refused from +1 more Gen3 x4 M.2 which is fine for me (still have Gen3 x3 support in addtion to the Gen3 x4). I went to ASUS again after my ASRock let me down on another system (CAPS obviously weak not holding initial power, system requires 2x start to run). So a bit more quality in the mainboard is a good way to go, imho.
So, thatās what I can share from my POV Have a great time with your new machine! I am sure it will rock!
Couldnāt agree more - I finally switched to RME about a year ago - and was sorry for not having done that sooner. Specifically Iām using the Digiface USB, which is a pure Audio Interface. It allows me to keep my DA/AD conversion separately and use ADAT over TOSLink cables to hook up the analog 
ADAT conversion units to the RME.
This approach allowed be to keep using my Steinberg MR816csx with its nice Yamaha pre-amps for analog ADAT conversion (and I also have an old Presonus DigiMax FS box that gives me another 8 channels of analog ADAT conversion).
In addition to impressively low latency, the RME ASIO driver on Windows is multi-client, i.e. it can be used by multiple pieces of software simultaneously. Steinberg themselves have never pulled that off (with the exception of a little unsupported experimental software some years ago).
Curious - how do you find the latency across multiple ADATs? I keep looking at the digiface as itās such an affordable way of getting on the RME wagon and offers an immense array of I/O.
Like you, i would use my current interface as a slave to it, plus an additional 8 pre ADAT. But i just canāt believe USB will deliver a performance close to my current Firewire or PCIe cards - both no longer supported - so iām on borrowed time and need to change.
I think itās the fact that thereās no internal ins/outs that worries me, everything is running via the I/Os - and iāve yet to speak to anyone who owns the digiface as it seems other models are vastly more popular.
From everything Iāve read analog ADAT conversion is generally in the sub millisecond range. So it adds less latency than being 2 meters from your guitar amp speaker.
So eventually ended up with the following,
11900K,
Asus Z590 Rog Strix F (only because there was a bundle with this in stock, didnt need a Rog Strix),
32GB 3200 RAM
WD SN850 M.2 (1gb 7KMbs)
BeQuiet Dark Rock Pro 4 Dual Tower
Bequiet 600w Pure Power 11 CM
Corsair 275Q case
Need to add another drive as 1GB is virtually full already.
Congratulations on your nice new rig - and thanks for sharing what you ended up with!
With the various supply shortages these days, it really limits the options, which in a weird way can also be a good thing.
Fortunately it seems that SSDs are not in short supply, so expanding your storage shouldnāt be much of a problem.
Wow, I even found some documentation about your storage:
"IBM introduced the first hard disk drive to break the 1GB barrier in 1980. It was called the IBM 3380 and could store 2.52GB (ā2.52 billion characters of information,ā according to IBM). Its cabinet was about the size of a refrigerator and the whole thing weighed in at 550 pounds (250 kg). It gave users rapid access to a large amount of data, thanks to transferring information at three million characters per second."
Where did you find it?
Sorry, couldnāt help myself, looks like a great new rig, have fun!
Cheers,
Benji
Oops, I had to read your post 3 times before I realised what I had done lol.
Will be adding another m.2 gen 4 1TB drive and an SSD for back up soon.
So I am running the above with Cubase 11 Pro and Windows 10. The whole thing is running terribly.
If i drop the buffer to 64 I get drop out and the meters shoot up. This is even with only a few tracks with data on them. However I am using a template which has preloaded something like 16 x KK, 8 x Halion, 8 x Omnisphere, 8 xKorg legacy, 24 Audio with 2 fx sends on each (reverb and delay). Surely my specs should allow me to run this kind of project without issue. Even at 128 buffer I constantly max out on the meters. I want to re-install with windows 11 but seems most of the Native Instrument stuff is not yet listed as compatible. Any thoughts?
They might not do. I donāt know what kk is but some instruments are a lot more power hungry than others.