No signal into Cubase 11

Hi there…
We have a problem here…
I have RME UFX 2 and Cubase 11. Everything was working all the time without any serious problem for really long time.
But at the moment i can not record anything into my DAW. Simply i can not get any signal- In Totalmix i see all and i hear all ( my synth connected to rme) But it looks like there is some wall between Rme an Cubase. I reinstall the drivers, update to new os ( Monterey) and still nothing. I dont see any blocked permissions in preference…really strange
Any ideas welcome


Make sure, the correct ASIO driver is selected in the Studio > Studio Setup > Audio System.

Make sure Cubase has enabled Mic in the System Preferences, please.
Open macOS System Preferences > Security & Privacy > Privacy > Microphone. Enable Cubase here.

This was first thing i did…no effect at all. I just realise that no any sound is coming out from my Cubase projects. Other media aplication works well…