Nuendo 8.1.10 keeps crashing on the launch!

My Mac Nuendo 8.1.10 keeps crashing on the launch!
Before it hangs on when exit. I have no more words but check the crash report!
I have many projects now and I am thinking why I choose Nuendo for working!

----------------------Crash Report by MacOS------------------------
Process:               Nuendo 8 [1662]
Path:                  /Applications/Nuendo 8.app/Contents/MacOS/Nuendo 8
Identifier:            com.steinberg.nuendo8
Version:               8.1.10.352 (8.1.10.352)
Code Type:             X86-64 (Native)
Parent Process:        ??? [1]
Responsible:           Nuendo 8 [1662]
User ID:               501

Date/Time:             2018-04-28 11:56:04.412 +0900
OS Version:            Mac OS X 10.13.4 (17E199)
Report Version:        12
Anonymous UUID:        B1C70542-1FF8-0AC1-20C2-6A48BDBFA787


Time Awake Since Boot: 1500 seconds

System Integrity Protection: enabled

Crashed Thread:        0  Dispatch queue: com.apple.main-thread

Exception Type:        EXC_BAD_ACCESS (SIGSEGV)
Exception Codes:       KERN_INVALID_ADDRESS at 0x0000000000000018
Exception Note:        EXC_CORPSE_NOTIFY

Termination Signal:    Segmentation fault: 11
Termination Reason:    Namespace SIGNAL, Code 0xb
Terminating Process:   exc handler [0]

VM Regions Near 0x18:
--> 
    __TEXT                 000000010b757000-000000010e8b3000 [ 49.4M] r-x/rwx SM=COW  /Applications/Nuendo 8.app/Contents/MacOS/Nuendo 8

Application Specific Information:
objc_msgSend() selector name: release


Thread 0 Crashed:: Dispatch queue: com.apple.main-thread
0   libobjc.A.dylib               	0x00007fff63120e9d objc_msgSend + 29
1   com.apple.Foundation          	0x00007fff3db136c0 -[_NSActivityAssertion dealloc] + 66
2   libobjc.A.dylib               	0x00007fff63124087 (anonymous namespace)::AutoreleasePoolPage::pop(void*) + 817
3   com.apple.CoreFoundation      	0x00007fff3b9f1a56 _CFAutoreleasePoolPop + 22
4   com.apple.Foundation          	0x00007fff3db168ad -[NSAutoreleasePool drain] + 144
5   com.steinberg.nuendo8         	0x000000010d1dd799 0x10b757000 + 27813785
6   com.steinberg.nuendo8         	0x000000010d57abd7 0x10b757000 + 31603671
7   com.steinberg.nuendo8         	0x000000010d3aad6d 0x10b757000 + 29703533
8   com.steinberg.nuendo8         	0x000000010d19341b 0x10b757000 + 27509787
9   com.steinberg.nuendo8         	0x000000010d1932a7 0x10b757000 + 27509415
10  com.steinberg.nuendo8         	0x000000010d1972cb 0x10b757000 + 27525835
11  libdyld.dylib                 	0x00007fff63d48015 start + 1

Thread 1:: CRASH THREAD
0   libsystem_kernel.dylib        	0x00007fff63e8f25e semaphore_timedwait_trap + 10
1   com.steinberg.nuendo8         	0x000000010d1b24b2 0x10b757000 + 27636914
2   com.steinberg.nuendo8         	0x000000010d1b346c 0x10b757000 + 27640940
3   com.steinberg.nuendo8         	0x000000010c82825e 0x10b757000 + 17633886
4   com.steinberg.nuendo8         	0x000000010d1b20af 0x10b757000 + 27635887
5   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 2:: CVDisplayLink
0   libsystem_kernel.dylib        	0x00007fff63e98a1e __psynch_cvwait + 10
1   libsystem_pthread.dylib       	0x00007fff64061589 _pthread_cond_wait + 732
2   com.apple.CoreVideo           	0x00007fff3d5fca44 CVDisplayLink::runIOThread() + 660
3   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
4   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
5   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 3:: com.steinberg.dispatcher.0
0   libsystem_kernel.dylib        	0x00007fff63e98a96 __psynch_rw_rdlock + 10
1   libsystem_pthread.dylib       	0x00007fff64065872 _pthread_rwlock_lock_wait + 56
2   libsystem_pthread.dylib       	0x00007fff6406580c _pthread_rwlock_lock_slow + 523
3   com.steinberg.nuendo8         	0x000000010d1c3287 0x10b757000 + 27705991
4   com.steinberg.nuendo8         	0x000000010d1c4ba1 0x10b757000 + 27712417
5   com.steinberg.nuendo8         	0x000000010d5aebbd 0x10b757000 + 31816637
6   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 4:: com.steinberg.dispatcher.1
0   libsystem_kernel.dylib        	0x00007fff63e98a96 __psynch_rw_rdlock + 10
1   libsystem_pthread.dylib       	0x00007fff64065872 _pthread_rwlock_lock_wait + 56
2   libsystem_pthread.dylib       	0x00007fff6406580c _pthread_rwlock_lock_slow + 523
3   com.steinberg.nuendo8         	0x000000010d1c3287 0x10b757000 + 27705991
4   com.steinberg.nuendo8         	0x000000010d1c4ba1 0x10b757000 + 27712417
5   com.steinberg.nuendo8         	0x000000010d5aebbd 0x10b757000 + 31816637
6   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 5:: com.steinberg.dispatcher.2
0   libsystem_kernel.dylib        	0x00007fff63e98a96 __psynch_rw_rdlock + 10
1   libsystem_pthread.dylib       	0x00007fff64065872 _pthread_rwlock_lock_wait + 56
2   libsystem_pthread.dylib       	0x00007fff6406580c _pthread_rwlock_lock_slow + 523
3   com.steinberg.nuendo8         	0x000000010d1c3287 0x10b757000 + 27705991
4   com.steinberg.nuendo8         	0x000000010d1c4ba1 0x10b757000 + 27712417
5   com.steinberg.nuendo8         	0x000000010d5aebbd 0x10b757000 + 31816637
6   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 6:: com.steinberg.dispatcher.3
0   libsystem_kernel.dylib        	0x00007fff63e98a96 __psynch_rw_rdlock + 10
1   libsystem_pthread.dylib       	0x00007fff64065872 _pthread_rwlock_lock_wait + 56
2   libsystem_pthread.dylib       	0x00007fff6406580c _pthread_rwlock_lock_slow + 523
3   com.steinberg.nuendo8         	0x000000010d1c3287 0x10b757000 + 27705991
4   com.steinberg.nuendo8         	0x000000010d1c4ba1 0x10b757000 + 27712417
5   com.steinberg.nuendo8         	0x000000010d5aebbd 0x10b757000 + 31816637
6   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 7:: com.steinberg.dispatcher.4
0   libsystem_kernel.dylib        	0x00007fff63e98a96 __psynch_rw_rdlock + 10
1   libsystem_pthread.dylib       	0x00007fff64065872 _pthread_rwlock_lock_wait + 56
2   libsystem_pthread.dylib       	0x00007fff6406580c _pthread_rwlock_lock_slow + 523
3   com.steinberg.nuendo8         	0x000000010d1c3287 0x10b757000 + 27705991
4   com.steinberg.nuendo8         	0x000000010d1c4ba1 0x10b757000 + 27712417
5   com.steinberg.nuendo8         	0x000000010d5aebbd 0x10b757000 + 31816637
6   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 8:: com.steinberg.dispatcher.5
0   libsystem_kernel.dylib        	0x00007fff63e98a96 __psynch_rw_rdlock + 10
1   libsystem_pthread.dylib       	0x00007fff64065872 _pthread_rwlock_lock_wait + 56
2   libsystem_pthread.dylib       	0x00007fff6406580c _pthread_rwlock_lock_slow + 523
3   com.steinberg.nuendo8         	0x000000010d1c3287 0x10b757000 + 27705991
4   com.steinberg.nuendo8         	0x000000010d1c4ba1 0x10b757000 + 27712417
5   com.steinberg.nuendo8         	0x000000010d5aebbd 0x10b757000 + 31816637
6   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 9:: com.steinberg.dispatcher.6
0   libsystem_kernel.dylib        	0x00007fff63e98a96 __psynch_rw_rdlock + 10
1   libsystem_pthread.dylib       	0x00007fff64065872 _pthread_rwlock_lock_wait + 56
2   libsystem_pthread.dylib       	0x00007fff6406580c _pthread_rwlock_lock_slow + 523
3   com.steinberg.nuendo8         	0x000000010d1c3287 0x10b757000 + 27705991
4   com.steinberg.nuendo8         	0x000000010d1c4ba1 0x10b757000 + 27712417
5   com.steinberg.nuendo8         	0x000000010d5aebbd 0x10b757000 + 31816637
6   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 10:: com.steinberg.dispatcher.7
0   libsystem_kernel.dylib        	0x00007fff63e98a96 __psynch_rw_rdlock + 10
1   libsystem_pthread.dylib       	0x00007fff64065872 _pthread_rwlock_lock_wait + 56
2   libsystem_pthread.dylib       	0x00007fff6406580c _pthread_rwlock_lock_slow + 523
3   com.steinberg.nuendo8         	0x000000010d1c3287 0x10b757000 + 27705991
4   com.steinberg.nuendo8         	0x000000010d1c4ba1 0x10b757000 + 27712417
5   com.steinberg.nuendo8         	0x000000010d5aebbd 0x10b757000 + 31816637
6   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 11:: com.steinberg.dispatcher.manager
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   libdispatch.dylib             	0x00007fff63d1e8e3 _dispatch_sema4_wait + 16
2   libdispatch.dylib             	0x00007fff63d169c9 _dispatch_semaphore_wait_slow + 101
3   com.steinberg.nuendo8         	0x000000010d5aee13 0x10b757000 + 31817235
4   com.steinberg.nuendo8         	0x000000010d1c3e56 0x10b757000 + 27709014
5   com.steinberg.nuendo8         	0x000000010d5aebbd 0x10b757000 + 31816637
6   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 12:
0   libsystem_kernel.dylib        	0x00007fff63e98a1e __psynch_cvwait + 10
1   libsystem_pthread.dylib       	0x00007fff64061589 _pthread_cond_wait + 732
2   libc++.1.dylib                	0x00007fff61ca6cb0 std::__1::condition_variable::wait(std::__1::unique_lock<std::__1::mutex>&) + 18
3   com.apple.JavaScriptCore      	0x00007fff3f67d736 void std::__1::condition_variable_any::wait<std::__1::unique_lock<bmalloc::Mutex> >(std::__1::unique_lock<bmalloc::Mutex>&) + 86
4   com.apple.JavaScriptCore      	0x00007fff3f67d3eb bmalloc::Scavenger::threadRunLoop() + 251
5   com.apple.JavaScriptCore      	0x00007fff3f67d1e9 bmalloc::Scavenger::threadEntryPoint(bmalloc::Scavenger*) + 9
6   com.apple.JavaScriptCore      	0x00007fff3f67d528 void* std::__1::__thread_proxy<std::__1::tuple<std::__1::unique_ptr<std::__1::__thread_struct, std::__1::default_delete<std::__1::__thread_struct> >, void (*)(bmalloc::Scavenger*), bmalloc::Scavenger*> >(void*) + 40
7   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
8   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
9   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 13:: Video Diascope
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.steinberg.videoengine     	0x000000012af7258b 0x12adb2000 + 1836427
2   com.steinberg.videoengine     	0x000000012aebf3cd 0x12adb2000 + 1102797
3   com.steinberg.videoengine     	0x000000012af7185f 0x12adb2000 + 1833055
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 14:: Video Diascope
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.steinberg.videoengine     	0x000000012af7258b 0x12adb2000 + 1836427
2   com.steinberg.videoengine     	0x000000012aebf3cd 0x12adb2000 + 1102797
3   com.steinberg.videoengine     	0x000000012af7185f 0x12adb2000 + 1833055
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 15:
0   libsystem_kernel.dylib        	0x00007fff63e8f35a mach_wait_until + 10
1   com.apple.CoreServices.CarbonCore	0x00007fff3cc0ab14 MPDelayUntil + 12
2   com.apple.CoreServices.CarbonCore	0x00007fff3cc1507e Delay + 69
3   se.propellerheads.rewire.library	0x000000011905621d RWIsReWireMixerAppRunningImp + 31069
4   se.propellerheads.rewire.library	0x0000000119063c29 RWIsReWireMixerAppRunningImp + 86889
5   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
6   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
7   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 16:: FThread
0   libsystem_kernel.dylib        	0x00007fff63e99bf2 kevent + 10
1   com.steinberg.dolbyatmosadapterski	0x0000000131da739c 0x131d8b000 + 115612
2   com.steinberg.dolbyatmosadapterski	0x0000000131da6fec 0x131d8b000 + 114668
3   com.steinberg.dolbyatmosadapterski	0x0000000131da6c35 0x131d8b000 + 113717
4   com.steinberg.dolbyatmosadapterski	0x0000000131da55b9 0x131d8b000 + 107961
5   com.steinberg.dolbyatmosadapterski	0x0000000132033cef 0x131d8b000 + 2788591
6   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 17:: ThumbnailProvider
0   libsystem_kernel.dylib        	0x00007fff63e98a1e __psynch_cvwait + 10
1   libsystem_pthread.dylib       	0x00007fff64061589 _pthread_cond_wait + 732
2   com.steinberg.reconform       	0x0000000132d6c64b 0x132cd6000 + 616011
3   com.steinberg.reconform       	0x0000000132f2348d 0x132cd6000 + 2413709
4   com.steinberg.reconform       	0x0000000132d6d1a2 0x132cd6000 + 618914
5   com.steinberg.reconform       	0x0000000132d8bcca 0x132cd6000 + 744650
6   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
7   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
8   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 18:: ThumbnailProvider
0   libsystem_kernel.dylib        	0x00007fff63e98a1e __psynch_cvwait + 10
1   libsystem_pthread.dylib       	0x00007fff64061589 _pthread_cond_wait + 732
2   com.steinberg.reconform       	0x0000000132d6c64b 0x132cd6000 + 616011
3   com.steinberg.reconform       	0x0000000132f2348d 0x132cd6000 + 2413709
4   com.steinberg.reconform       	0x0000000132d6d1a2 0x132cd6000 + 618914
5   com.steinberg.reconform       	0x0000000132d8bcca 0x132cd6000 + 744650
6   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
7   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
8   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 19:
0   libsystem_kernel.dylib        	0x00007fff63e8f20a mach_msg_trap + 10
1   libsystem_kernel.dylib        	0x00007fff63e8e724 mach_msg + 60
2   com.apple.audio.midi.CoreMIDI 	0x00007fff3c7cbb83 XServerMachPort::ReceiveMessage(int&, void*, int&) + 93
3   com.apple.audio.midi.CoreMIDI 	0x00007fff3c7e29a0 MIDIProcess::RunMIDIInThread() + 336
4   com.apple.audio.midi.CoreMIDI 	0x00007fff3c7f3c8e XThread::RunHelper(void*) + 10
5   com.apple.audio.midi.CoreMIDI 	0x00007fff3c7f7e7b CAPThread::Entry(CAPThread*) + 77
6   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
7   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
8   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 20:
0   libsystem_kernel.dylib        	0x00007fff63e99292 __workq_kernreturn + 10
1   libsystem_pthread.dylib       	0x00007fff64060009 _pthread_wqthread + 1035
2   libsystem_pthread.dylib       	0x00007fff6405fbe9 start_wqthread + 13

Thread 21:
0   libsystem_kernel.dylib        	0x00007fff63e99292 __workq_kernreturn + 10
1   libsystem_pthread.dylib       	0x00007fff6406020e _pthread_wqthread + 1552
2   libsystem_pthread.dylib       	0x00007fff6405fbe9 start_wqthread + 13

Thread 22:: VST Loader
0   libsystem_kernel.dylib        	0x00007fff63e8f252 semaphore_wait_signal_trap + 10
1   com.steinberg.nuendo8         	0x000000010d1b23b2 0x10b757000 + 27636658
2   com.steinberg.nuendo8         	0x000000010ceb3e0d 0x10b757000 + 24497677
3   com.steinberg.nuendo8         	0x000000010d1b20af 0x10b757000 + 27635887
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 23:: VST Loader
0   libsystem_kernel.dylib        	0x00007fff63e8f252 semaphore_wait_signal_trap + 10
1   com.steinberg.nuendo8         	0x000000010d1b23b2 0x10b757000 + 27636658
2   com.steinberg.nuendo8         	0x000000010ceb3e0d 0x10b757000 + 24497677
3   com.steinberg.nuendo8         	0x000000010d1b20af 0x10b757000 + 27635887
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 24:: VST Loader
0   libsystem_kernel.dylib        	0x00007fff63e8f252 semaphore_wait_signal_trap + 10
1   com.steinberg.nuendo8         	0x000000010d1b23b2 0x10b757000 + 27636658
2   com.steinberg.nuendo8         	0x000000010ceb3e0d 0x10b757000 + 24497677
3   com.steinberg.nuendo8         	0x000000010d1b20af 0x10b757000 + 27635887
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 25:: VST Loader
0   libsystem_kernel.dylib        	0x00007fff63e8f252 semaphore_wait_signal_trap + 10
1   com.steinberg.nuendo8         	0x000000010d1b23b2 0x10b757000 + 27636658
2   com.steinberg.nuendo8         	0x000000010ceb3e0d 0x10b757000 + 24497677
3   com.steinberg.nuendo8         	0x000000010d1b20af 0x10b757000 + 27635887
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 26:: VST Loader
0   libsystem_kernel.dylib        	0x00007fff63e8f252 semaphore_wait_signal_trap + 10
1   com.steinberg.nuendo8         	0x000000010d1b23b2 0x10b757000 + 27636658
2   com.steinberg.nuendo8         	0x000000010ceb3e0d 0x10b757000 + 24497677
3   com.steinberg.nuendo8         	0x000000010d1b20af 0x10b757000 + 27635887
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 27:: VST Loader
0   libsystem_kernel.dylib        	0x00007fff63e8f252 semaphore_wait_signal_trap + 10
1   com.steinberg.nuendo8         	0x000000010d1b23b2 0x10b757000 + 27636658
2   com.steinberg.nuendo8         	0x000000010ceb3e0d 0x10b757000 + 24497677
3   com.steinberg.nuendo8         	0x000000010d1b20af 0x10b757000 + 27635887
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 28:: VST Preloader
0   libsystem_kernel.dylib        	0x00007fff63e8f25e semaphore_timedwait_trap + 10
1   com.steinberg.nuendo8         	0x000000010d1b24b2 0x10b757000 + 27636914
2   com.steinberg.nuendo8         	0x000000010ceb4f8e 0x10b757000 + 24502158
3   com.steinberg.nuendo8         	0x000000010ceb4154 0x10b757000 + 24498516
4   com.steinberg.nuendo8         	0x000000010d1b20af 0x10b757000 + 27635887
5   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 29:: Video Preload
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.steinberg.videoengine     	0x000000012af7258b 0x12adb2000 + 1836427
2   com.steinberg.videoengine     	0x000000012ae900cc 0x12adb2000 + 909516
3   com.steinberg.videoengine     	0x000000012af7185f 0x12adb2000 + 1833055
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 30:: Video Playback
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.steinberg.videoengine     	0x000000012af7258b 0x12adb2000 + 1836427
2   com.steinberg.videoengine     	0x000000012ade26de 0x12adb2000 + 198366
3   com.steinberg.videoengine     	0x000000012af7185f 0x12adb2000 + 1833055
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 31:: Video Buffer
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.steinberg.videoengine     	0x000000012af7258b 0x12adb2000 + 1836427
2   com.steinberg.videoengine     	0x000000012ade26de 0x12adb2000 + 198366
3   com.steinberg.videoengine     	0x000000012af7185f 0x12adb2000 + 1833055
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 32:: Timer
0   libsystem_kernel.dylib        	0x00007fff63e8f25e semaphore_timedwait_trap + 10
1   com.steinberg.nuendo8         	0x000000010d1b24b2 0x10b757000 + 27636914
2   com.steinberg.nuendo8         	0x000000010cbfb548 0x10b757000 + 21644616
3   com.steinberg.nuendo8         	0x000000010d1b20af 0x10b757000 + 27635887
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 33:: Baios Processing Thread
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.steinberg.baios           	0x0000000112f71515 0x112f48000 + 169237
2   com.steinberg.baios           	0x0000000112f5b584 0x112f48000 + 79236
3   com.steinberg.baios           	0x0000000112f7059f 0x112f48000 + 165279
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 34:: com.apple.audio.IOThread.client
0   libsystem_kernel.dylib        	0x00007fff63e8f20a mach_msg_trap + 10
1   libsystem_kernel.dylib        	0x00007fff63e8e724 mach_msg + 60
2   com.apple.audio.CoreAudio     	0x00007fff3b4898da HALB_MachPort::SendMessageWithReply(unsigned int, unsigned int, unsigned int, unsigned int, mach_msg_header_t*, bool, unsigned int) + 124
3   com.apple.audio.CoreAudio     	0x00007fff3b48984d HALB_MachPort::SendSimpleMessageWithSimpleReply(unsigned int, unsigned int, int, int&, bool, unsigned int) + 45
4   com.apple.audio.CoreAudio     	0x00007fff3b4868b9 HALC_ProxyIOContext::IOWorkLoop() + 977
5   com.apple.audio.CoreAudio     	0x00007fff3b48631c HALC_ProxyIOContext::IOThreadEntry(void*) + 128
6   com.apple.audio.CoreAudio     	0x00007fff3b48605e HALB_IOThread::Entry(void*) + 72
7   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
8   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
9   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 35:: ASIOX Thread
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.steinberg.CoreAudio2ASIO  	0x0000000111e81bd5 0x111e72000 + 64469

Thread 36:: LRThread
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.steinberg.vst3.pluginset.nuendo	0x000000012c58c86b 0x12c10e000 + 4712555
2   com.steinberg.vst3.pluginset.nuendo	0x000000012c3e26d4 0x12c10e000 + 2967252
3   com.steinberg.vst3.pluginset.nuendo	0x000000012c58b4df 0x12c10e000 + 4707551
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 37:: CIThread
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.steinberg.vst3.pluginset.nuendo	0x000000012c58c86b 0x12c10e000 + 4712555
2   com.steinberg.vst3.pluginset.nuendo	0x000000012c3e26d4 0x12c10e000 + 2967252
3   com.steinberg.vst3.pluginset.nuendo	0x000000012c58b4df 0x12c10e000 + 4707551
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 38:: AudioCalc
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.ableton.live-engine       	0x000000012f32f0e8 LLocalSingleSyncPoint::Wait() + 40
2   com.ableton.live-engine       	0x000000012f34777a OAudioCalcThread::SSlaveThreadFunction(TUserData) + 106
3   com.ableton.live-engine       	0x000000012f33d481 void* std::__1::__thread_proxy<std::__1::tuple<void (TThread::*)(), TThread*> >(void*) + 113
4   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
5   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
6   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 39:: AudioCalc
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.ableton.live-engine       	0x000000012f32f0e8 LLocalSingleSyncPoint::Wait() + 40
2   com.ableton.live-engine       	0x000000012f34777a OAudioCalcThread::SSlaveThreadFunction(TUserData) + 106
3   com.ableton.live-engine       	0x000000012f33d481 void* std::__1::__thread_proxy<std::__1::tuple<void (TThread::*)(), TThread*> >(void*) + 113
4   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
5   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
6   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 40:: AudioCalc
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.ableton.live-engine       	0x000000012f32f0e8 LLocalSingleSyncPoint::Wait() + 40
2   com.ableton.live-engine       	0x000000012f34777a OAudioCalcThread::SSlaveThreadFunction(TUserData) + 106
3   com.ableton.live-engine       	0x000000012f33d481 void* std::__1::__thread_proxy<std::__1::tuple<void (TThread::*)(), TThread*> >(void*) + 113
4   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
5   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
6   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 41:: AudioCalc
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.ableton.live-engine       	0x000000012f32f0e8 LLocalSingleSyncPoint::Wait() + 40
2   com.ableton.live-engine       	0x000000012f34777a OAudioCalcThread::SSlaveThreadFunction(TUserData) + 106
3   com.ableton.live-engine       	0x000000012f33d481 void* std::__1::__thread_proxy<std::__1::tuple<void (TThread::*)(), TThread*> >(void*) + 113
4   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
5   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
6   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 42:: AudioCalc
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.ableton.live-engine       	0x000000012f32f0e8 LLocalSingleSyncPoint::Wait() + 40
2   com.ableton.live-engine       	0x000000012f34777a OAudioCalcThread::SSlaveThreadFunction(TUserData) + 106
3   com.ableton.live-engine       	0x000000012f33d481 void* std::__1::__thread_proxy<std::__1::tuple<void (TThread::*)(), TThread*> >(void*) + 113
4   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
5   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
6   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 43:: AudioCalc
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.ableton.live-engine       	0x000000012f32f0e8 LLocalSingleSyncPoint::Wait() + 40
2   com.ableton.live-engine       	0x000000012f34777a OAudioCalcThread::SSlaveThreadFunction(TUserData) + 106
3   com.ableton.live-engine       	0x000000012f33d481 void* std::__1::__thread_proxy<std::__1::tuple<void (TThread::*)(), TThread*> >(void*) + 113
4   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
5   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
6   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 44:: AudioCalc
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.ableton.live-engine       	0x000000012f32f0e8 LLocalSingleSyncPoint::Wait() + 40
2   com.ableton.live-engine       	0x000000012f34777a OAudioCalcThread::SSlaveThreadFunction(TUserData) + 106
3   com.ableton.live-engine       	0x000000012f33d481 void* std::__1::__thread_proxy<std::__1::tuple<void (TThread::*)(), TThread*> >(void*) + 113
4   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
5   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
6   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 45:
0   libsystem_kernel.dylib        	0x00007fff63e8f20a mach_msg_trap + 10
1   libsystem_kernel.dylib        	0x00007fff63e8e724 mach_msg + 60
2   com.apple.CoreFoundation      	0x00007fff3ba337d5 __CFRunLoopServiceMachPort + 341
3   com.apple.CoreFoundation      	0x00007fff3ba32b27 __CFRunLoopRun + 1783
4   com.apple.CoreFoundation      	0x00007fff3ba321a3 CFRunLoopRunSpecific + 483
5   com.apple.CoreFoundation      	0x00007fff3ba70c33 CFRunLoopRun + 99
6   com.celemony.melodyne.rewiredevice	0x00000001306fb09b 0x1305a0000 + 1421467
7   com.celemony.melodyne.rewiredevice	0x00000001306d2f0a 0x1305a0000 + 1257226
8   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 46:
0   libsystem_kernel.dylib        	0x00007fff63e8f246 semaphore_wait_trap + 10
1   com.celemony.melodyne.rewiredevice	0x00000001306f068f 0x1305a0000 + 1377935
2   com.celemony.melodyne.rewiredevice	0x00000001305bb75c 0x1305a0000 + 112476
3   com.celemony.melodyne.rewiredevice	0x00000001306d2f0a 0x1305a0000 + 1257226
4   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 47:
0   libsystem_kernel.dylib        	0x00007fff63e8f20a mach_msg_trap + 10
1   libsystem_kernel.dylib        	0x00007fff63e8e724 mach_msg + 60
2   se.propellerheads.reason.engine	0x0000000130ca1db8 0x1308f6000 + 3849656
3   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
4   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
5   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 48:: Reason ReWire mode idle thread
0   libsystem_kernel.dylib        	0x00007fff63e98d8a __semwait_signal + 10
1   libsystem_c.dylib             	0x00007fff63e13724 nanosleep + 199
2   libsystem_c.dylib             	0x00007fff63e13618 usleep + 53
3   se.propellerheads.reason.engine	0x00000001309fbf4c 0x1308f6000 + 1072972
4   se.propellerheads.reason.engine	0x0000000130bc0a97 0x1308f6000 + 2927255
5   libsystem_pthread.dylib       	0x00007fff64060661 _pthread_body + 340
6   libsystem_pthread.dylib       	0x00007fff6406050d _pthread_start + 377
7   libsystem_pthread.dylib       	0x00007fff6405fbf9 thread_start + 13

Thread 49:: MB Scanner
0   libsystem_kernel.dylib        	0x00007fff63e9a14a read + 10
1   com.steinberg.mediaservice    	0x000000012689d72b 0x126806000 + 620331
2   com.steinberg.mediaservice    	0x00000001268857df 0x126806000 + 522207
3   com.steinberg.mediaservice    	0x00000001268a6dfe 0x126806000 + 658942
4   com.steinberg.mediaservice    	0x00000001268ad7c6 0x126806000 + 686022
5   com.steinberg.mediaservice    	0x00000001268ad68e 0x126806000 + 685710
6   com.steinberg.mediaservice    	0x00000001268cc2fc 0x126806000 + 811772
7   com.steinberg.mediaservice    	0x00000001268b25c7 0x126806000 + 705991
8   com.steinberg.mediaservice    	0x000000012688b228 0x126806000 + 545320
9   com.steinberg.mediaservice    	0x0000000126878203 0x126806000 + 467459
10  com.steinberg.mediaservice    	0x000000012685738f 0x126806000 + 332687
11  com.steinberg.mediaservice    	0x000000012684233b 0x126806000 + 246587
12  com.steinberg.mediaservice    	0x0000000126834ff3 0x126806000 + 192499
13  com.steinberg.mediaservice    	0x0000000126834246 0x126806000 + 188998
14  com.steinberg.mediaservice    	0x000000012683b54c 0x126806000 + 218444
15  com.steinberg.mediaservice    	0x00000001269f4cb9 0x126806000 + 2026681
16  com.steinberg.mediaservice    	0x000000012699d10f 0x126806000 + 1667343
17  libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 50:: MB Database Writer
0   libsystem_kernel.dylib        	0x00007fff63e98d8a __semwait_signal + 10
1   libsystem_c.dylib             	0x00007fff63e13724 nanosleep + 199
2   libsystem_c.dylib             	0x00007fff63e13586 sleep + 41
3   com.steinberg.mediaservice    	0x0000000126882bba 0x126806000 + 510906
4   com.steinberg.mediaservice    	0x000000012689c5ba 0x126806000 + 615866
5   com.steinberg.mediaservice    	0x000000012687bc0a 0x126806000 + 482314
6   com.steinberg.mediaservice    	0x000000012687c0dc 0x126806000 + 483548
7   com.steinberg.mediaservice    	0x0000000126845ff1 0x126806000 + 262129
8   com.steinberg.mediaservice    	0x000000012699d10f 0x126806000 + 1667343
9   libsystem_pthread.dylib       	0x00007fff64063ae0 _pthread_suspended_body + 229

Thread 0 crashed with X86 Thread State (64-bit):
  rax: 0x0000000000000010  rbx: 0x000060c001684c40  rcx: 0x0100000000000000  rdx: 0x0040000000000000
  rdi: 0x00000001363c3838  rsi: 0x00007fff39c5ce91  rbp: 0x00007ffee44a85d0  rsp: 0x00007ffee44a85a8
   r8: 0x00006000000c0c00   r9: 0x0000000000000040  r10: 0x0000000000000000  r11: 0x00007fff39c5ce91
  r12: 0xa3a3a3a3a3a3a3a3  r13: 0x0000000000000000  r14: 0x00007fefad826038  r15: 0x00007fefad826000
  rip: 0x00007fff63120e9d  rfl: 0x0000000000010246  cr2: 0x0000000126963f37
  
Logical CPU:     0
Error Code:      0x02000003
Trap Number:     133



Model: iMac16,2, BootROM IM162.0218.B00, 4 processors, Intel Core i7, 3.3 GHz, 16 GB, SMC 2.32f20
Graphics: Intel Iris Pro Graphics 6200, Intel Iris Pro Graphics 6200, Built-In
Memory Module: BANK 0/DIMM0, 8 GB, DDR3, 1867 MHz, 0x80AD, 0x483943434E4E4E434C544D4C41522D4E5544
Memory Module: BANK 1/DIMM0, 8 GB, DDR3, 1867 MHz, 0x80AD, 0x483943434E4E4E434C544D4C41522D4E5544
AirPort: spairport_wireless_card_type_airport_extreme (0x14E4, 0x156), Broadcom BCM43xx 1.0 (7.77.37.29.1a7)
Bluetooth: Version 6.0.5f3, 3 services, 27 devices, 1 incoming serial ports
Network Service: Ethernet, Ethernet, en0
PCI Card: pci137a,7, Video, Thunderbolt@195,0,0
Serial ATA Device: APPLE HDD ST1000LM024, 1 TB
USB Device: USB 3.0 Bus
USB Device: USB3.0 Hub
USB Device: Touro Mobile 3.0
USB Device: RS-EC32-U3R
USB Device: USB3.0 Hub
USB Device: USB3.0 Hub
USB Device: USB3.0 Hub
USB Device: JMS56x Series
USB Device: Bluetooth USB Host Controller
USB Device: FaceTime HD Camera (Built-in)
USB Device: USB2.0 Hub
USB Device: USB2.0 Hub
USB Device: USB2.0 Hub
USB Device: USB2.0 Hub
USB Device: iLok
USB Device: eLicenser
USB Device: KOMPLETE KONTROL S88
USB Device: Maschine Jam
USB Device: nanoKONTROL2
Thunderbolt Bus: iMac, Apple Inc., 27.4
Thunderbolt Device: 828x, MOTU, 3, 7.7

Does it happen if you run Nuendo in Safe Start Mode?
https://www.steinberg.net/nc/en/support/knowledgebase_new/show_details/kb_show/safe-start-mode-resetting-the-cubase-preferences.html

At present, do not run Nuendo 8 on Mac OS 10.13. Many problems are on the operating system. I change the system back to 10.12.6, basically all problems are avoided.